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What to Know About LSD Use What Is LSD?

LSD (lysergic acid diethylamide) is a long-acting psychoactive drug that alters and distorts perceptions and feelings. LSD is one of the most powerful mood-altering drugs available in uncontrolled situations. It causes long-lasting distortions in a person's perception of reality. Although LSD's popularity peaked in the 1960s and 1970s, the drug has been there since 1938, when it was first synthesized. Ergot, a fungus that keeps growing on grains like rye, was used to create it. LSD is a Schedule I drug in many countries, making it illegal. This indicates that the drug has a strong risk of abuse. LSD is a hallucinogenic substance; therefore, it can alter one's consciousness, emotions, and thoughts.

How to Recognize LSD

LSD is commonly accessible in tablet or capsule form, although it is also found in liquid form. The liquid is occasionally divided up and placed on absorbent paper, known as “window pane” or “blotter” acid.

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How Does LSD Work?

According to scientists, LSD works by altering receptors involved in the control of serotonin, a neurotransmitter found in the brain. Serotonin governs mood, motor control, sensory perception, appetite, body temperature, and sexual activity, among other behavioral, perceptual, and regulatory systems.

When LSD affects this process, it can cause significant distortions in a person’s view of reality or hallucinations.

1 LSD users experience images, sounds, and feelings that seem genuine but aren’t.

These sensory hallucinations can be accompanied by strong emotional swings. As a result, an LSD “trip” can quickly transition from a delightful to a horrifying experience, rendering the drug’s effect extremely unpredictable.

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What the Experts Say

Despite the fact that LSD has been around for over 70 years, there are few, if any, well-controlled research studies on the effects of the drug on the brains of people who use it. Smaller studies and case studies make up the research that really does exist.

According to a study of LSD research undertaken over the previous 25 years, LSD is the most effective form of the drug as it improves emotional empathy but inhibits terror recognition. It has therapeutic effects, but additional research is needed. It increases sentiments of connectedness and trust in others, as well as interconnectedness in some brain networks, making people more receptive to suggestions.


LSD alters the brain’s neurotransmitters, resulting in a variety of consequences that aren’t fully understood. People frequently experience emotional changes, such as enhanced empathy and feelings of connectedness to others, in particular with respect to altered perception.

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Use of LSD

Despite the possible hazards, people utilize LSD for a variety of reasons. The hallucinatory effects can appear to be enjoyable. People often derive a sense of distinctiveness or inventiveness due to the drug’s warped views and hallucinations, as if they are attaining knowledge they could not reach without it.

The trouble with LSD users is that all of these effects, whether happy or terrible, are unpredictable. The same dose of LSD from the same batch might have radically different effects on different people. Furthermore, a person’s reaction to the same dose and type of LSD can vary from one trip to the next or from experience to another.

Off-Label Uses

While LSD is not legally prescribed, research into its therapeutic potential is underway, with some promising results. According to studies, the substance promotes neuron growth and could be useful in treating drug addiction, depression, and post-traumatic stress disorder (PTSD).

In a 2014 trial, a small group of patients with anxiety were given LSD-assisted psychotherapy. The findings suggested that LSD could be beneficial at lowering anxiety when given in such a controlled context; however, more research is needed.

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Common Side Effects of LSD

Researchers in smaller case studies have described some of the most striking effects of LSD, including:

  1. Changed perceptions of oneself and time
  2. Synesthesia (crossing senses such as seeing sound or hearing colors)
  3. Sensations and moods alter dramatically.
  4. Experiencing many feelings at the same time
  5. Rapidly shifting from one emotion to the next (mood swing)

Panic might result from these altered perceptions and experiences. Some people have terrible ideas, despairing sensations, fears of losing control, insanity, and death. Having a “poor trip” refers to several kinds of events.

Scientists have also been stumped as to why some LSD users suffer flashbacks or the unexpected repetition of features of an LSD trip. These flashbacks might occur as soon as a few days after the substance was first used or as long as a year afterward.

Loss of appetite, insomnia, tremors, dry mouth, convulsions, and nausea are all physical adverse effects of LSD use.

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Signs of LSD Use

Because the signs of LSD usage are distinct, you might be able to tell if someone is using it.

The following are some of the most prevalent indications of LSD use:

  1. Paranoia or anxiety
  2. Strange remarks
  3. Convulsions
  4. pupils dilated
  5. Disorientation
  6. Skin that has been washed
  7. Hallucinations
  8. Body temperature has risen.
  9. Paraphernalia or Miscellaneous (tablets, sugar cubes, blotter paper, or gelatin)
  10. Appetite problems
  11. Incoherent, rambling speech

Panic attacks, psychosis, convulsions, and delusions are symptoms of an LSD overdose. If you suspect someone has overdosed on LSD, call 911 as soon as possible and try to keep the person calm until aid arrives.

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LSD Tolerance, Dependence, and Withdrawal

LSD is not a physically addictive substance, although it does cause tolerance with continuous usage. When people become accustomed to a drug, they require more to obtain similar results. This is especially risky with LSD because tolerance develops rapidly, and the impacts of the substance are often unpredictable.

Tolerance to LSD dissipates rapidly, typically within 72 hours. As a result, people may unknowingly use a potentially toxic or deadly dose of the chemical.


Incidentally,  LSD  is not addictive, and most people become bored of it and either stop using it or gradually reduce their use.

While LSD does not cause physical dependence or addiction, it does have the potential to cause psychological dependence. People will frequently seek the substance to alleviate or eliminate the painful symptoms of psychological withdrawal.


Unlike many other drugs,  LSD withdrawal is rarely followed by a slew of unpleasant bodily symptoms. Many people can cease using LSD without experiencing unpleasant physical However; psychological symptoms can be extremely common and include:

  1. Anxiety
  2. Depression
  3. Confusion 
  4. Hallucinations
  5. Mood swings
  6. Concentration problems
  7. Psychosis
  8. Suicidal ideation


LSD is indeed not addictive, but it can cause tolerance, which means that users will need to consume even more of the drug to have the same results.

How long does it take LSD to leave your system?

About 20 to 90 minutes after consuming LSD, people start to feel its effects. These effects can continue for up to 12 hours, with the individual returning to their regular state, taking up to 24 hours.

Urine tests can detect LSD usage for up to 5 days, while hair follicle testing can detect it for up to 90 days.

Does LSD use result in mental health issues?

Some people may ask if LSD consumption causes mental health issues. Psychedelic substances (which include LSD, psilocybin, and mescaline) have not been connected to the emergence of mental health disorders, even though they can generate some dramatic, short-term psychological effects. Researchers concluded that psychedelic usage is not an independent risk factor for mental health issues such as anxiety and depression. 5 However, LSD usage may increase the risk of hallucinogen-induced perceptual problems (HPPD).

How to Get Help

LSD abuse can have devastating consequences for both users and their loved ones. Outpatient and residential treatment options are available, and they may include cognitive-behavioral therapy (CBT), individual counseling, family therapy, and group therapy.

While there are no drugs to treat LSD usage, other medications can be used to treat depression, anxiety, and other psychiatric problems.


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